This randomized, double-blind, placebo-controlled study conducted in 80 women aged 45 and older and with amenorrhea of > 12 months with vasomotor symptoms (hot flashes and/or night sweats). Women were randomized to receive either 250 mg of standardized soy extract equal to 100 mg/day of isoflavones or placebo for 10 months. There were 40 women […]
Category Archive for 'Soy'
The aim of this study was to determine if long-term isoflavone soy protein (ISP) in supplement form, could affect endometrial thickness (lining of the uterus), endometrial hyperplasia (potentially precancerous cells of the lining of the uterus) and endometrial cancer in postmenopausal women. This randomized, double-blind, placebo-controlled trial matched 350 postmenopausal women ages 45-92 with a […]
Soy and hot flashes
Posted in Menopause, Phytoestrogen, Soy on Aug 14th, 2012
The purpose of this analysis was to determine whether soy isoflavones were effective in the alleviation of hot flashes in perimenopausal and postmenopausal women. Two large data bases, PubMed and the Cochrane Controlled Clinical Trials Register Database were searched for studies on this topic that were double-blind randomized controlled trials through mid December 2010. A […]
Data from the Women’s Healthy Eating and Living (WHEL) was used to examine the effect of soy intake on breast cancer prognosis in 3,088 breast cancer survivors. These women were early stage breast cancer patients who were followed for an average of 7.3 years. Soy isoflavone intakes were measured after the diagnosis with a food […]
A meta-analysis of five case-control and two cohort studies examined the effects of soy intake on endometrial and ovarian cancer. 169,051 women and, 3516 with endometrial or ovarian cancer in the U.S., China, Italy and Japan with an average age of 54 were evaluated for their soy intake based on soy containing foods or soy […]
Soy as a Prevention Strategy for Osteoporosis
Posted in Bone Health, General, Menopause, Phytoestrogen, Soy on Mar 18th, 2009
The potential for soy protein or soy isoflavones to alter bone metabolism and bone resorption is currently contradictory and inconclusive. The lack of agreement in the literature is thought to be related to variations in study design. These variations in study design include differences in the dosage and form of soy products studied, (i.e. soy […]
Soy Isoflavone supplementation improves menopause symptoms only in equol producers
Posted in Menopause, Phytoestrogen, Soy on May 31st, 2008
This randomized, double-blind, placebo-controlled clinical trial with 96 menopausal women was conducted over 6 months. 66 women were given 135 mg of soy isoflavone and 30 women were given placebo. After one week, the women in the treatment group were tested and further divided into 2 subgroups, equol-producing (EP) and non equol-producing (non-EP), according to […]
Soy as a prevention strategy for Osteoporosis
Posted in Bone Health, Bone Loss, Calcium, Nutrition, Prevention, Soy on Mar 30th, 2008
The potential for soy protein or soy isoflavones to alter bone metabolism and bone loss is currently contradictory and inconclusive. Our two best measurements are bone density testing with DXA (an xray test) measures or bone metabolism markers. The lack of agreement in the literature is thought to be related to variations in study design […]
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