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Archive for the 'Cancer Prevention' Category

Breast cancer rates had been steadily climbing since the 1940s until about 2002 [1] but breast cancer rates decreased by about 2% between 1998 and 2007 in the U.S.[2] However, this decrease was only among women aged 50 and older. One of the more news worthy items has been a significant decline in breast cancer [...]

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Premenopausal women appear to be more sensitive at detecting breast cancer when done during the first week of the menstrual cycle (day 1 of the menses to day 7) in women with a history of screening mammograms. Researchers analyzed 387,218 screening mammograms in premenopausal women that were associated with 1,283 breast cancers. Greater sensitivity was [...]

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Vitamin D and Ovarian Cancer Risk Reduction

Women with ovarian cancer and control subjects were analyzed for their vitamin D status as measured by serum 25(OH)D3 level in 7,243 women from the National Health and Nutrition Examination Surveys (NHANES). A high and low status of levels of serum vitamin D was defined as above or below 23 ng/mL (57.5 nmol/L). After adjusting [...]

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A new publication from the Women’s Health Initiative (WHI) focused on the effects of estrogen and progestin (conjugated equine estrogens 0.625 mg/day and 2.5mg/day medroxyprogesterone acetate = Prempro) on breast cancer incidence mortality after an average follow-up of 11 years, through August 2009. The new information from this now 11 year body of information translates [...]

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Reference: Anderson L, Cotterchio M, Vieth R, Knight J. Vitamin D and calcium intakes and breast cancer risk I npre- and postmenopausal women. Am J Clin Nutr 2010; 91(6): 1699-1701. A recent study on vitamin D and breast cancer risk was published that once  again points the way to vitamin D as a safe and [...]

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This prospective study of 512 women with early breast cancer evaluated the role of serum vitamin D levels as a potential factor influencing breast cancer prognosis. The average age was 50 and the average vitamin D levels was 58.1 nmol/L. Vitamin D levels were deficient (<50 nmol/L) in 192 women, insufficient (50 to 72 nmol/L) [...]

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36,282 postmenopausal women were enrolled in a Women’s Health Initiative clinical trial to determine the effects of calcium and vitamin D on the incidence of hip fracture. Invasive breast cancer was a secondary outcome measure. Patients were randomly assigned to 1000 mg of calcium with 400 IU of vitamin D3 daily, or placebo for an [...]

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In a population-based study, 1180 Caucasian women older than 55, were randomized to receive a calcium supplement , a calcium supplement plus 1100 IU of vitamin D (cholecalciferol), or a daily placebo. Health status and compliance to the regimen were assessed every 6 months over 4 years and serum vitamin D was measured at baseline [...]

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The Women’s Healthy Eating and Living (WHEL) study is a multi-center, randomized controlled trial studying a total of 3088 women diagnosed with early stage breast cancers –stage I-IIIa who were diagnosed within the previous four years. Subjects in the WHEL study were randomized into either a treatment group, who’s diet consisted of; a daily dose [...]

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In a population-based study, 1180 Caucasian women older than 55, were randomized to receive a daily placebo, calcium or calcium plus 1000 IU of vitamin D (cholecalciferol). Â Health status and compliance to the regimen were assessed every 6 months over 4 years and serum vitamin D was measured at baseline and annually. 1024 women [...]

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