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Archive for the 'St. John’s wort' Category

St. John’s wort products and extracts have been used for a wide range of medical conditions, the most common being depressive disorders. The most robust research is in the area of mild to moderate depression, with some additional research in anxiety, severe depression, seasonal affective disorder, premenstrual syndrome, and perimenopause/menopause. St. John’s wort is the […]

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St. John’s Wort and Menopause

Several studies of St. John’s wort alone and St. John’s wort with black cohosh have been able to demonstrate that these products are good options for perimenopausal and menopausal women with hot flashes, mood issues, sleep problems and quality of life. In the newest of the St. John’s wort studies in perimenopausal/menopausal women, a total […]

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The results of a randomized, double-blind, placebo-controlled crossover trial using St. John’s Wort for PMS sufferers were recently published. 36 women with regular menstrual cycles who were diagnosed with mild PMS were randomly assigned to receive St. John’s Wort tablets (900 mg/day and standardized to 0.18% hypericin and 3.38% hyperforin) or placebo for two menstrual […]

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The objective of this study was to evaluate the effectiveness of a combination of St. John’s wort and chaste tree berry in the treatment of PMS-like symptoms in peri-menopausal women. This clinical trial was conducted over 16 weeks and information was collected at 4 week intervals rating PMS scores in peri-menopausal women who were experiencing […]

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SJW and Perimenopause

This double-blind, randomized clinical trial, studied the effect of Hypericum perforatum extract (St. John’s wort extract) compared with placebo, on symptoms and quality of life of 47 symptomatic perimenopausal women aged 40 to 65 with three or more hot flashes per day. Women were randomly assigned to receive a St. John’s wort extract (900 mg […]

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St. John’s Wort and menopause symptoms St John’s wort was compared with a placebo in a double-blind, randomized clinical trial on symptoms and quality of life issues in perimenopausal women. Forty-seven 40 to 65 y.o. perimenopausal women who experienced three or more hot flashes per day were randomized to receive either 900 mg three times […]

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St. John’s Wort and Oral Contraceptives

Sixteen healthy women who had taken a low dose oral contraceptive (OC) with 20 mcg ethinylestradiol + 0.15 mg desogesterol for at least 3 months participated in this study. A 50% ethanol extract of St. John’s wort 250 mg twice daily standardized to 0.2% hypericin (1 mg/day) and < 0.2%(< 1mg/day) hyperforin was initiated day […]

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This was a prospective, non-randomized, open-label observational study conducted over two years, in Germany. The purpose of the study was to evaluate the use, safety and effectiveness of black cohosh alone or in combination with St. John’s wort on menopausal symptoms. 6141 women at 1287 outpatient gynecology offices were treated with recommended doses of black […]

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